Enhancement and Prolongation of Babesia microti Infections in Mice Infected with Oncogenic Viruses
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چکیده
منابع مشابه
Downregulation of hepatic cytochrome P450 3A in mice infected with Babesia microti.
To investigate effects of Babesia infection on drug metabolism, we intraperitoneally inoculated B. microti into ICR mice and measured the expression and activity of hepatic cytochrome P450 (CYP) 3A, a major drug-metabolizing enzyme. Twelve days after infection, CYP3A11 mRNA, CYP3A protein and activity and mRNAs of nuclear receptors, which participate in CYP3A expression, were significantly redu...
متن کاملBabesia microti: parasitaemia and antibody responses to primary and challenge infections in BALB/c mice.
Babesia microti (Franca, 1909), an intraerythrocytic, ticktransmitted haemoprotozoan parasite is a common pathogen of free-living small mammals, particularly rodents. Babesiosis caused by this species of Babesia is gaining increasing interest as emerging zoonosis in humans (Parry M.F., Fox M., Burka S.A., Richar W.J. 1977: J. Am. Vet. Med. Assoc. 238: 1282– 1283; Homer M.J., Aguilar-Delfini, Te...
متن کاملBabesia microti primarily invades mature erythrocytes in mice.
Babesia microti is a tick-borne red blood cell parasite that causes babesiosis in people. Its most common vertebrate reservoir is the white-footed mouse. To determine whether B. microti invades reticulocytes, as does the canine pathogen B. gibsoni, we infected the susceptible inbred mouse strains C.B-17.scid and DBA/2 with a clinical isolate of B. microti. Staining of fixed permeabilized red bl...
متن کاملHematological findings and antibody responses in Syrian hamster (Mesocricetus auratus) infected with Babesia microti.
Hematological findings during the course of infection and the antibody response in Syrian hamsters infected with Babesia microti were examined. A macrocytic hypochromic anemia with an increase of the reticulocyte count was detected as a rise in the parasitized erythrocyte rate. White blood cell counts also remarkedly increased with the increases of both neutrophils and active-shaped monocytes, ...
متن کاملBabesia microti, Upstate New York
Five cases of human babesiosis were reported in the Lower Hudson Valley Region of New York State in 2001. An investigation to determine if Babesia microti was present in local Ixodes scapularis ticks yielded 5 positive pools in 123 pools tested, the first detection of B. microti from field-collected I. scapularis in upstate New York.
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ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1972
ISSN: 0022-1287
DOI: 10.1099/00221287-72-1-79